Sodium Deoxycholate 302-95-4

Function:

(1) Historically sodium deoxycholate was used as an intermediate for the production of corticosteroids,

     which have anti-inflammatory indications.

(2) It is used in the preparation and formulation of certain microbiological diagnostic media.

(3) An emerging use of sodium deoxycholate acid is as a biological detergent to lyse cells

     and solubilise cellular and membrane components.

(4) Popular anionic, bile-acid detergent for many laboratory uses

(5) Effective in disrupting and dissociating many types of protein interaction

(6) Useful for elution or regeneration of certain kinds of affinity columns

(7) It is most frequently used as a component of cell lysis buffers (e.g., RIPA buffer),

    but also has been used for liposome preparation, isolation of membrane proteins and lipids,

     preventing nonspecific binding in affinity chromatography and a cell culture media supplement.