Galantamine Hydrobromide 1953-04-4

Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase(AChE) inhibitor (IC50 = 410 nM)

and allosteric potentiator at neuronal nicotinic ACh receptors. IC50 Value: 410 nM Target:

AChEGalanthamine hydrobromide prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells.

Long-term administration reduces amyloid precursor protein deposition and neurodegeneration in a mouse model

of Alzheimer's disease.